Wave Life Sciences USA, Inc.→
Formulations, Oligonucleotide Synthesis… at Wave Life… · Lexington
Job Description
Wave Life Sciences is a biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health. Our RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation and deep insights in human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Our toolkit of RNA-targeting modalities including RNAi silencing and RNA editing provides us with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. Our diversified pipeline is focused on our obesity, alpha-1 antitrypsin deficiency and PNPLA3 I148M liver disease programs and includes clinical programs for Duchenne muscular dystrophy and Huntington’s disease, as well as several preclinical programs utilizing our versatile RNA medicines platform. Driven by the calling to “Reimagine Possible”, we are leading the charge toward a world in which human potential is no longer hindered by the burden of disease.
Wave Life Sciences seeks a highly motivated co-op student to join its team of Small Scale Synthesis, Oligonucleotide Synthesis and Chemistry scientists in Lexington, Massachusetts. This co-op student will gain exposure to areas of oligonucleotide synthesis, formulation, purification, and analysis. The co-op will be trained in a variety of laboratory techniques and instrumentation, making this an excellent learning opportunity for future entrance into industry or academia. This is an ideal position for any student with strong organizational skills and attention to detail who thrives in a team-oriented, fast-paced and multi-disciplinary biotech environment. Completion of coursework in organic chemistry required with biochemistry, analytical chemistry and laboratory experience is preferred. This is an ideal position for an individual with an interest in analytical chemistry who thrives in a team-oriented, fast-paced, biotech environment. This candidate will be responsible for fulfilling compound requests to support Discovery-related activities and ensuring sample quality.
RESPONSIBILITIES
- Analyze oligonucleotides by LC-MS, UHPLC, endotoxin, osmolality, UV and pH
- Prepare/formulate oligonucleotide samples for in vitro and in vivo biological assays and method development
- Use automated liquid handler (Hamilton Star) for high throughput plate-based sample preparation
- Assist with management of the oligonucleotide inventory and re-QC program
- Record and present data in an electronic laboratory notebook (ELN)
- Gain exposure to automated oligonucleotide solid-phase synthesis techniques
- Gain exposure to liquid chromatography method development and application
QUALIFICATIONS
- Currently enrolled in an undergraduate or graduate science program in Chemistry, Biology, Biotechnology or related field
- Coursework in organic chemistry is required, biochemistry and analytical chemistry is a plus
- Understanding of laboratory best practices and safety protocols
- Attention to detail and well organized
- Laboratory experience with common laboratory operations including pipetting, weighing, and centrifugation preferred
- Enthusiasm for DNA/RNA therapeutic development
The range provided is based on what we believe is a reasonable estimate for the annual base salary pay range for this position at the time of posting. Actual annual base salary will vary based on several factors including, but not limited to, relevant skills, experience, qualifications, position criticality, and internal equity. This position is eligible for a discretionary annual bonus and discretionary stock-based long-term incentives. In addition to compensation, Wave offers a comprehensive and competitive range of benefits designed to support our employees’ and their families physical and financial health and overall well-being. These include, but are not limited to, company-sponsored medical, dental, vision, life, long and short-term disability insurances, generous paid time off (including a week-long company shutdown in the Summer and the Winter), 401K participation with matching contributions, and Employee Stock Purchase Program. Wave Life Sciences provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability or genetics. In addition to federal law requirements, Wave Life Sciences complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.
Wave Life Sciences expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status. Improper interference with the ability of Wave Life Sciences’ employees to perform their job duties may result in discipline up to and including discharge.
We value our relationships with professional recruitment firms. To protect the interests of all parties, and given the large volume of inquiries received from third-party placement agencies, we are not able to respond to all agency inquiries. We do not accept unsolicited resumes from any source other than directly from candidates for current or future positions. Submission of unsolicited resumes in advance of a signed agreement between our company and a placement agency does not create an implied obligation and, if an unsolicited candidate represented by a placement agency is hired, we are not obligated to pay a fee. Only approved recruitment firms will be allowed to provide services to Wave Life Sciences, USA.
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