Senior Director, US New Product Planning at Vertex… · Boston

Senior Director, US New Product Planning
Location: 5000 - Vertex US - Fan Pier
Job Description
General Summary:
We are seeking a Senior Director, US New Product Planning, to help shape the future of our pipeline and build the foundation for successful US launches. This is a highly visible leadership role for a strategic, commercially minded, and pragmatic leader who thrives at the intersection of asset strategy, US market planning, and enterprise capability building.
This role is ideal for someone who has worked in both the US business and on global teams, and who understands what it takes to succeed in the US market across functions—not just within a single discipline. The individual will represent the US perspective for early pipeline assets, including assets approximately 3 to 4 years from launch, and help ensure that strategic decisions made today translate into successful launches tomorrow.
Importantly, this role offers the opportunity to help build a new Business Unit for the organization. As the pipeline advances, this leader will help define the commercial foundation, capability needs, operating model, and resourcing approach required to establish a successful future US business.
Key Responsibilities
Represent the US commercial perspective on global asset teams for early pipeline assets, especially those approximately 3 to 4 years from launch
Lead development of US commercial strategy in partnership with global commercial, medical, market access, HEOR, analytics, operations, and finance
Translate asset strategy into a clear US launch blueprint, including:
market development priorities
launch scenarios and key assumptions
capability requirements
organization design implications
field force and non-personal promotion considerations
budget and investment needs
Identify and frame key strategic choices related to:
positioning
patient finding and market development
access and reimbursement readiness
evidence generation priorities
customer engagement model
patient services and support strategy
Develop milestone-based and scenario-based plans that prepare the organization for launch well before traditional pre-launch planning begins
Partner with cross-functional leaders to define the capabilities, talent, processes, and infrastructure needed for launch success
Assess organizational readiness and recommend how to build, buy, or borrow required capabilities
Provide strategic input on US commercialization models, including implications for specialty, institution-based, and buy-and-bill markets
Support governance and executive decision-making with clear recommendations, tradeoffs, and risk assessments
Help ensure a smooth transition from early planning into launch readiness and in-market execution
Help define the strategic and organizational foundations of a new Business Unit
Required Experience
Significant experience in biotech or pharmaceutical commercial strategy, new product planning, marketing, launch strategy, or related roles
Meaningful experience in both:
US commercial/business roles
global or enterprise asset/team roles
Demonstrated success in new product planning, pre-launch strategy, or launch planning
Deep experience in neurology and/or rare disease
Strong understanding of US commercialization in complex specialty markets, including buy-and-bill dynamics and related access, site-of-care, and reimbursement considerations
Experience building or shaping resourcing plans, operating models, and capability roadmaps
Proven ability to influence senior stakeholders and lead through a matrixed environment
Strong track record of cross-functional collaboration across commercial, medical, market access, analytics, operations, finance, and patient services
Preferred Experience
Experience in US commercial planning, brand leadership, or business leadership
Experience serving on a global asset team or in a global commercial strategy role
Experience in specialty markets and complex launch environments
Experience supporting assets from development through launch readiness
Experience with provider-administered therapies and commercialization models involving buy-and-bill
Critical Capabilities
Enterprise thinking — sees beyond function and understands the full set of enablers required for US launch success
US market insight — understands customer, access, evidence, reimbursement, and operational realities in the US
Cross-functional integration — connects perspectives across teams to create practical, aligned plans
Launch planning excellence — translates strategic choices into launch milestones, readiness plans, and execution requirements
Organizational and capability planning — defines what talent, structure, and capabilities will be needed over time
Executive communication — distills complexity into clear, compelling recommendations
Pragmatic decision-making — operates effectively under uncertainty and turns ambiguity into action
Why This Role Stands Out
This is a unique opportunity to influence some of the most important decisions in the pipeline—before launch planning is fully formed and while strategic choices can still shape outcomes.
You will have the chance to:
shape the future of the US business
influence asset strategy at an early stage
work across US and global leadership
define how the organization prepares for future launches
help build the foundation of a new Business Unit, including strategic priorities, capabilities, and organizational readiness
bring both strategic rigor and practical judgment to high-impact decisions
Success in This Role Looks Like
The US perspective is incorporated early and meaningfully into asset strategy
Strategic choices are translated into actionable US launch and capability plans
Leadership has clear visibility into risks, tradeoffs, and investment needs
The organization is better prepared for launch—earlier, more thoughtfully, and with greater alignment
Cross-functional teams are aligned around a practical path to US success
The role contributes meaningfully to the build-out of a new Business Unit
Pay Range:
$228,000 - $342,000
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1.    Hybrid: work remotely up to two days per week; or select
2.    On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com