Scientist I, Neuroimmunology, Target… at Valo Health · Lexington

Summary: Valo Health is a human-centric, AI-enabled biotechnology company working to make new drugs for patients faster. They are looking for a Scientist I to play a pivotal role in the experimental validation of targets for neurodegenerative diseases and support drug discovery program goals. Responsibilities: - Generate experimental plans and execute at the bench to enable validation of novel therapeutic targets - Develop and execute human functional cell-based assays in immune and neuroinflammatory cell types to enable characterization of novel drug targets - Perform experiments and generate data in the laboratory with a high degree of reliability, efficiency, and accuracy to support target validation projects - Work in collaboration with other Valo scientists to progress target validation and drug development aligned with company goals - Generate data with high quality standards and document within an electronic lab notebook - Stay current on emerging trends and advancements in the field Required Qualifications: - A PhD in Biological Sciences or a related field with 0-2+ years of experience (or MS with 4+ years of experience or a BS with 6+ years of experience) - Expertise in one or more of the following areas: Immunology, Autoimmune Disease, Neuroimmunology, Neuroinflammation - This position requires experience in immune and inflammatory mechanisms and models - Experience in human in vitro systems including direct cell culture with immune cell types (e.g. PMBCs, blood-based cancer cell lines, iPSCs derived immune cells), molecular biology, and genetic manipulation - Experience in assay development with functional readouts (cytokine profiling, inflammatory signaling, flow cytometry, phagocytosis, cell death assay, cellular function) - Strong oral and written communication, presentation and interpersonal skills - Track record of impactful scientific contributions as demonstrated by high impact publications - Experience collaborating with multidisciplinary teams Preferred Qualifications: - Experience in human in vitro systems including cell culture and functional assays involving neuroinflammatory cells and/or neurons - Experience working in in vivo/ex vivo systems - Experience in discovery stage preclinical drug discovery programs and with target validation projects Required Skills: Immunology, Autoimmune Disease, Neuroimmunology, Neuroinflammation, Immune, inflammatory mechanisms, models, Human in vitro systems, Cell culture, Molecular biology, Genetic manipulation, Assay development, Cytokine profiling, Inflammatory signaling, Flow cytometry, Phagocytosis, Cell death assay, Cellular function assays, vivo systems, Ex vivo systems, Preclinical drug discovery, Target validation Benefits: Healthcare coverage, Annual incentive program, Retirement benefits, A broad range of other benefits