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Life Science Research Professional 1 at Stanford… · Stanford
Skills
Job Description
Applying a comprehensive understanding for the theories and methods of a life science discipline, perform work directly involved in research projects, interpreting results and participation in experimental design.
The Mourrain Lab, within the Department of Psychiatry & Behavioral Sciences at Stanford University’s School of Medicine, is seeking a full time Life Science Research Professional 1 (LSRP 1) to study sleep and its effects on neurobiology. The Mourrain Lab specializes in neuroscience, genetics, epigenetics, developmental biology, and engineering to achieve the following objectives:
- Investigate the reasons behind sleep and how it enhances cognitive performance by altering synaptic connections.
- Identify and address synaptic deficits observed in neurodevelopmental conditions like Fragile X syndrome, Autism, neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and age-related synaptic changes.
- Study genes and processes essential for neuronal regeneration to repair damaged brain tissue, including the retina.
- Enhance knowledge of gene regulation mechanisms and explore the impact of non-coding Single Nucleotide Polymorphisms (SNPs) on causing human diseases.
The LSRP 1 will test the impact of sleep disruptions and sleep interventions on autophagosomal activity and cellular redox homeostasis mechanisms. The LSRP will perform CRISPR/Cas9 editing of genes involved in lysosomal and phagosome activity. They will perform molecular analysis of the generated mutations and biochemical phenotyping.
DESIRED QUALIFICATIONS:
- Bachelor’s degree in Molecular Biology, Biochemisty or related field or MSc desired
- Prior experience performing biology/gene editing, biochemistry related to oxidative stress, and animal biology.
Responsibilities
Core Duties:
- Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
- Independently conduct experiments; maintain detailed records of experiments and outcomes.
- Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
- Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
- Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
- Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
- Assist with orientation and training of new staff or students on lab procedures or techniques.
Minimum Education andExperience
Bachelor's degree in related scientific field.
Knowledge, Skills and Abilities:
- General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
- Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
- Ability to maintain detailed records of experiments and outcomes.
- General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
- Ability to work under deadlines with general guidance.
- Excellent organizational skills and demonstrated ability to accurately complete detailed work.