Co-op: Analytical Development at Prime Medicine, Inc. in Cambridge, MA

Summary: Prime Medicine is a leading biotechnology company focused on gene editing therapies. They are seeking a co-op for the Fall 2026 cycle to join their analytical development team, where the candidate will participate in the development of analytical methods and assist in various projects related to gene editing therapeutic drug development. Responsibilities: - Participate in separation-based method (HPLC, LC-MS) development to assess lipid nanoparticle (LNP) drug products and their components. Assist senior-level scientists with buffer preparation, maintenance of instruments, and developing up-to-date analytical methods that help to increase in-process analytics capacity - Participate in cell-based method (flow cytometry) development to assess cell therapy drug products. Support the maintenance of instruments - Support the phase-appropriate product development (PD) sample analyses, release testing, and stability studies for the characterization and release of cell and gene therapy drug products, drug substances, and critical raw materials - Document, present, and communicate experimental data and conclusions in an electronic notebook, following cGMP documentation practices - Data analysis, interpretation, and presentation within the team Required Qualifications: - Currently enrolled in a B.S. or M.S. program in biochemistry, chemistry, chemical engineering, pharmaceutical science, or a related field - Basic knowledge of separation sciences and technologies - Ability to handle multiple projects in a fast-paced environment - Excellent troubleshooting and communication skills - Ability to work independently and within a team - Skilled in documenting findings and activities in comprehensive reports and ensuring proper inventory of materials and analytical equipment Preferred Qualifications: - Hands-on experience with LC-MS, capillary electrophoresis, and/or cell culture is preferred - Previous co-op experience in the biotechnology industry - Independently motivated, detail-oriented, and excellent problem-solving abilities Required Skills: HPLC, LC-MS, Capillary electrophoresis Important Skills: Flow cytometry, Separation sciences Nice-to-Have Skills: Troubleshooting Benefits: Robust health, financial, and wellness benefits—including medical, dental, vision, life insurance, a 401(k) match, and equity programs, Generous paid time off, Wellness days, Company-wide recharge breaks