Software Engineer - .NET Full Stack Developer at Mayo Clinic… · Remote

Summary: Mayo Clinic Rochester is seeking a Software Engineer to design, develop, and maintain .NET-based back-end services for genomics and clinical applications. The role involves building and optimizing services for genomic workflows and collaborating with cross-functional teams to ensure high performance and reliability of the systems. Responsibilities: - Designing and implementing services aligned to enterprise architecture, including cloud-ready APIs, data integration pipelines, and secure interoperability layers for genomic systems - Building and optimizing services that handle complex genomic workflows, large-scale clinical datasets, and high-throughput data processing - Ensuring that all services meet strict performance, reliability, and accuracy requirements, scale effectively as data volumes grow, and remain resilient within hybrid cloud ecosystems - Participating in Agile and DevOps practices using GitHub, Azure DevOps (ADO), Azure Pipelines, and CI/CD frameworks - Maintaining comprehensive technical documentation, contributing to code reviews, and participating in expert-level troubleshooting through log analysis, root cause evaluation, and data/system investigation Required Qualifications: - Bachelor's degree in computer science/engineering or related field; Or an associate's degree in computer science/engineering or related field with an additional 2 years of experience as described below - Have working knowledge and experience of Software Engineering with a minimum of internships and a minimum of 1 year of experience, or 2 years of experience coding applications or services in a high-level language (C, C++, Golang, Java, C# etc.) - Demonstrated problem solving and time management skills - Possesses strong technical aptitude for designing and implementing software solutions - Experience with modern application development frameworks - Knowledge of professional software engineering practices & best practices for the full software development life cycle, including coding standards, code reviews, source control management, build processes, testing, and operations - Deep hands-on technical expertise, excellent verbal and written communication skills - Experience with Agile software development techniques Preferred Qualifications: - Experience developing applications in hybrid environments, including on-premises systems, Azure, and Google Cloud Platform (GCP) - Familiarity with building and integrating RESTful APIs, microservices, and web services using .NET technologies - Knowledge of DevOps pipelines and CI/CD using Azure DevOps, GitHub Actions, or Azure Pipelines - Utilization of AI coding tool such as GitHub CoPilot, Gemini, Claude - Experience with relational and NoSQL databases, analytics platforms, big-data processing, or enterprise data pipelines - Background in developing high-performance, scalable, and highly available distributed systems - Experience supporting or developing solutions in healthcare, clinical, Bioinformatics or genomics-focused applications is highly desirable - Ability to use a wide variety of open-source technologies and cloud-based services - Experience with Google and Azure cloud environments - Experience in databases, analytics, big data systems or business intelligence products - Experience with building high-performance, highly available and scalable distributed systems - Experience developing software for healthcare related industries Required Skills: Software Engineering, High-level programming languages, Modern application development frameworks, Software development life cycle, Agile software development, Hybrid environment development, Azure, Google Cloud Platform, RESTful APIs, Microservices, Web services, .NET technologies, DevOps pipelines, CI/CD, Relational databases, NoSQL databases, Big data processing, Distributed systems, Healthcare software development, Bioinformatics, Genomics applications