Supervisor Clinical Laboratory # 4798 (Night… at Grail · Durham

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

The Supervisor, Clinical Laboratory oversees day-to-day operations of assigned laboratory areas, ensuring accuracy, efficiency, and compliance with regulatory and organizational standards. This role provides direct supervision to laboratory associates and technical staff, coordinating workflow, monitoring quality, and fostering a culture of safety and accountability. The Supervisor partners with laboratory leadership to implement processes, support staff development, and ensure operational readiness.

This position is on the night shift working from 10:00pm to 8:30am EDT. You will work on-site full-time at our office located in Durham, NC

Responsibilities:

• Supervise daily laboratory operations, including sample processing, workflow coordination, and equipment utilization.
  • Provide direct supervision, coaching, and performance feedback to laboratory and support staff.
  • Verify that personnel are trained and deemed proficient prior to performing testing on patient specimens independently
  • Monitor staff adherence to standard operating procedures (SOPs), quality control measures, and regulatory requirements (e.g., CLIA, CAP, OSHA).
  • Ensure accuracy and timeliness of sample handling, testing support, and data documentation.
  • Initiate preventive and/or remedial actions when test procedures deviate from the laboratory's established performance specifications
  • In the event of nonconformances, ensuring that test results are not reported until corrective action has been taken and the test is performing according to laboratory established performance specifications
  • Manage scheduling, staffing, and workload distribution to meet operational priorities.
  • Direct onboarding, training, and competency assessments for new and existing staff.
  • Serve as escalation for troubleshooting complex operational and technical issues, escalating to higher management when necessary.
  • Maintain laboratory compliance with safety standards, including PPE use, hazardous waste handling, and emergency protocols.
  • Contribute to continuous improvement initiatives, recommending workflow optimizations and efficiency enhancements.
  • Prepare and review documentation for audits, inspections, and internal quality reviews.
  • Serve as a liaison between frontline staff and laboratory leadership, communicating goals, expectations, and updates.

These job duties are a summary of the primary duties and responsibilities of the job and position. It is not intended to be a comprehensive or all-inclusive listing of duties and responsibilities. Contents are subject to change at the company's discretion.

Required Qualifications:

• Bachelor’s degree in a science-related field (preferred), or equivalent combination of education and relevant experience.
  • Typically requires 6–8 years of relevant laboratory or technical experience, including prior team lead or supervisory responsibilities.
  • Knowledge of laboratory regulations, quality assurance practices, and safety standards.
  • Demonstrated level of knowledge regarding applicable regulatory standards commensurate with the position's complexity and scope, contributing to organizational regulatory compliance. Minimal applicable standards for this position include:
  • Clinical laboratory regulations (e.g. CAP, CLIA, NYSDOH, ISO 15189)
  • Operations within the regulated medical device environment (e.g. IVDD, IVDR, FDA 21 CFR 800 series, FDA 21 CFR Part 11)
  • Development and Operations within a regulated clinical study environment (e.g. ICH E6 (GCP), ISO 20916, FDA 21 CFR Part 11, Part 50, Part 54, Part 56)
  • Strong leadership and people management skills with the ability to supervise, mentor, and motivate staff.

Preferred Qualifications:

- Solid understanding of laboratory operations, sample handling, and equipment use.
- Effective communication skills, both verbal and written, for engaging with staff and leadership.
- Strong organizational and time-management skills with the ability to balance multiple priorities.
- Problem-solving and decision-making skills to resolve technical and operational issues.
- Commitment to maintaining quality and compliance in a regulated environment.

Physical Demands and Working Environment:

• Laboratory environment with routine exposure to biological samples and chemicals.
  • Requires frequent standing, walking, bending, and occasional lifting up to 40 lbs.
  • Mandatory use of PPE (lab coats, gloves, safety glasses) at all times in laboratory areas.
  • May require flexible work hours, including evenings, weekends, or holidays, to support operational needs.

The expected, full-time, annual base pay scale for this position is $80,000 - $106,000 . Actual base pay will consider skills, experience, and location.

This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.

GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at rc@grailbio.com if you require an accommodation to apply for an open position.

GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!