Constructor University (formerly Jacobs University) is a private, state-accredited, English-language university in Bremen. We offer Bachelor, Master, and PhD programs in three schools: School of Science, School of Computer Science and Engineering, and School of Business, Social and Decision Sciences. Our principles are first-class teaching and research, international diversity, and transdisciplinary cooperation. According to the 2024 Times Higher Education (THE) World University Rankings, Constructor University is among the top 25 percent out of more than 1900 universities worldwide and is ranked as the second most international university in the world. As an international university, we attract highly talented and open-minded students from all over the world. Currently, over 1,600 students from 110 nations live and study on our residential campus.

We invite applications from interested candidates for the following position, available immediately:

PhD position in Cellular Neurobiology (m/f/d)

(full time; 3 years)

Our recently established research group develops and studies human-relevant models for neurobiology. We use induced pluripotent stem cells to generate cell-based models of the human brain, so-called brain organoids. These 3D brain models allow us to study neurotoxicity, factors influencing neurodevelopment - such as sex hormones, environmental toxicants, and genetic or developmental disorders - and the mechanisms shaping early brain function.

About the PhD project:

In this project, you will generate and characterize human brain organoids from male and female donors and analyze their electrophysiological activity using multi-electrode array (MEA) technology. A central goal is to quantify electrophysiological network metrics and connect them to developmental trajectories within the organoids. You will investigate how the factors mentioned above affect early network formation, cellular differentiation, maturation, and functional connectivity in this model system.

Your profile:

• Motivated, reliable scientist with organizational and problem-solving skills
• Communicative, enthusiastic team player
• BSc and MSc in Biology, Neuroscience, Biochemistry, Bioinformatics, or related fields
• Hands-on experience in e.g. Cell Culture, Omics approaches or Molecular Biology
• Basic programming skills (e.g., Python or R) or motivation to learn
• Fluency in English is required; German skills are an advantage, primarily for interactions outside the lab

What you can expect at Constructor University:

We are an international, world-class private university embarking on an exciting journey of growth and expanding our portfolio. Join us and become a part of our global teams!

• Flexible working hours for work-life balance
• Individual onboarding, support, and development planning
• Corporate fitness with EGYM Well Pass (formerly Qualitrain)
• Green campus with extensive dining options and recreation areas, take the tour: Campus
• Constructor University has comprehensive sustainability and environmental programs

Constructor University unequivocally guarantees the academic freedom of every member of the faculty, as well as every other member of the Constructor University community. We encourage diversity in the University in ethnic, cultural, social, religious, political, and national backgrounds, as well as in individual lifestyle. Constructor University offers full equality of opportunity to all qualified applicants and is an equal opportunity employer.

Your application:

For any further information regarding this position, please contact Prof. Maren Schenke, via email (mschenke@constructor.university).

For your application, please upload a single PDF file (NameSurname.pdf) including:

(1) A motivation letter outlining your interest and suitability for the position

(2) A curriculum vitae

(3) A brief summary of previous research-related experience (max 1 page)

(4) Copies of certificates and diplomas

(5) Contact details of two academic referees

(6) Proof of English proficiency (optional)

Applications will be reviewed on a rolling basis until the position is filled. Please note that only applications submitted through the official application portal will be considered. Shortlisted candidates will be invited to online or in-person interviews.