TALENT PIPELINE - Principal Scientist (Process… at Cambrex · Durham

Company Information

You Matter to Cambrex.

Cambrex is a leading global contract development and manufacturing organization (CDMO) that provides drug substance development and manufacturing across the entire drug lifecycle, as well as comprehensive analytical and IND enabling services.

With over 40 years of experience and a team of 2,000 experts servicing global clients from North America and Europe, Cambrex offers a range of specialized drug substance technologies and capabilities, including continuous flow, controlled substances, liquid-phase peptide synthesis, solid-state science, material characterization, and highly potent APIs.

Your Work Matters.

At Cambrex, we strive to build a culture where all colleagues have the opportunity to:

• engage in work that matters to our customers and the patients they serve
• learn new skills and enjoy new experiences in an engaging and safe environment
• strengthen connections with coworkers and the community

We’re committed to attracting and nurturing a passionate team of valued professionals in our fast-paced and growing company. We offer a competitive benefits package that includes healthcare, life insurance, planning for retirement, and more!

Your Future Matters.

Known for our customer-focused scientific and manufacturing excellence, as well as our strong commitment to quality and safety, we offer a range of career and growth opportunities across our global network of locations. Together with our customers, we aim to improve the quality of life for patients around the world. Start a career where You Matter by applying today!

Overview:

• Design and carry out multistep organic syntheses, isolation, and purification of targeted
• products.
• Must possess a strong understanding of modern organic synthesis methodologies.
• Must have a thorough understanding of modern analytical and spectroscopic techniques and
• be able to interpret the corresponding data and spectra.
• Ability to conduct literature searches for specific target compounds and be able to use the
• literature to base a design of alternate routes to these compounds. Requires ongoing
• professional development to keep abreast of current scientific literature and discuss these
• findings with colleagues.
• Must demonstrate a proficiency to carry out laboratory syntheses and purification techniques
• on scales ranging from milligrams to several kilograms, and design and implement process
• modifications.
• Requires excellent time management with the ability to manage projects on-time without
• supervision.
• Ability to author and review comprehensive reports at the conclusion of projects for internal
• and customer use.
• Work closely with other chemistry and analytical laboratory staff to coordinate project activities
• and resource usage.
• Work to ensure that a spirit of teamwork and cooperation always exists within the group.
• Conduct laboratory operations in a safe manner. Maintain familiarity with the company’s
• chemical hygiene plan. Exhibit safety awareness and safe work practices.
• Follow responsible actions regarding chemical disposal. Maintain compliance with all
• regulations at the federal, state, and local levels.
• Must demonstrate effective communication skills (both interpersonal and presentations).
• Participate in project team meetings with customers.
• Work closely with manufacturing and GMP operations to coordinate project related equipment
• and activities.
• Maintain a clean, safe laboratory work area.

Responsibilities:

Position is directed toward optimization of existing chemical routes and development of alternate

chemistry toward key synthetic intermediates and APIs. Carries out multistep chemical synthesis and

product isolation/purification operations in the laboratory, independently or as part of an integrated

team. Chemist utilizes modern analytical tools to determine identity and purity of products made

during projects. Communication with clients in regular team meetings; prepares R&D reports at the

conclusion of projects

Qualifications / Skills:

Organic Chemistry Knowledge: Beginning to demonstrate an understanding of advanced theories in Organic

Chemistry/Process Development.

Cross Discipline Knowledge: Higher level of understanding of the principles of cross-functional departments,

including analytical chemistry and engineering.

GMP/Regulatory Knowledge: Demonstrated understanding of industrial GMP and practical application to

Cambrex programs; Some ability to provide feedback to clients re: clinical strategy.

Instrumentation: Advanced knowledge of HPLC, GC, MS, automated reactor platforms, In-situ reaction

monitoring, and ability to train and troubleshoot problems with equipment (and help others).

Communication: Good written and oral communication skills, ability to communicate with clients without

manager supervision.

Problem Solving: Strong demonstration of problem solving, ability to lead investigations.

Time Management: Able to maintain timeline of key activities and use time efficiently; ability to handle projects

without supervision, though requires regular check-in with manager.

Leadership: Demonstrated record of mentorship and development of peers, partner lines and ability to support

initiatives within the department.

Technical Documentation and Review: Ability to author and review key technical documents with minimal

RFT errors. Can write new SOP with manager assistance, keep current lab notebook while practicing GDP.

External Influence: Ability to lead local project teams and steer clients to desired outcomes; ability to work with

management to develop key local laboratory-based initiatives.

Industry Credibility and Rapport: Recognized scientific leader within the Cambrex organization, locally and

possibly beginning to extend to other sites.

Operational Excellence: Actively participates in key operational excellence initiatives.

Change Orientation: Active participation and support for implementation of Cambrex system level

changes/initiatives.

Education, Experience, and Licensing Requirements: (Text Only)

Ph.D. in Chemistry or related field with minimum 6 years’ experience or M.S. in Chemistry or related field with minimum 10 years’ experience or B.S. degree in Chemistry or related field with 14 years of experience in lab environment, pharmaceutical experience preferred. Hands on experience in pharmaceutical/chemical process development. Excellent verbal and written communication/interpersonal skills, organizational skills, and the ability to work in a diverse team environment are essential. Proficiency with Microsoft software (SharePoint, Word / EXCEL / PowerPoint), and Chemdraw is expected.