Process Engineering Associate II at BillionToOne in Austin, TX

Summary: BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. They are seeking a Process Engineering Associate II to drive process improvement, support technology transfer to a new lab in Austin, TX, and troubleshoot recurring errors to enhance clinical assay performance. Responsibilities: - Design, execute, and analyze wet lab experiments to improve process efficiency and assay reliability - Evaluate new molecular biology techniques and technologies to enhance assay performance - Perform complex manual and automated laboratory procedures (e.g. nucleic acid extraction, PCR, sequencing, reagent preparation) - Conduct assay validation studies to qualify new and improved assays for clinical use at both sites - Build data analysis and software tools to monitor process health, surface sources of error, and accelerate troubleshooting - Collaborate with the team to analyze complex data, diagnose issues, and implement solutions - Support technology transfer to our new Austin, TX CLIA lab to bring the new site online - Present project progress, data, and technical insights to the team and department Required Qualifications: - BS or MS in a relevant scientific or engineering discipline (e.g., Bioengineering, Chemical Engineering, Molecular Biology, Biochemistry, Chemistry, or Physics) - At least 1 year of hands-on lab research experience, including core molecular biology techniques (e.g., PCR, DNA/RNA extraction, sequencing) - Exceptional analytical reasoning and troubleshooting skills, with experience in data analysis (bioinformatics, statistical analysis, or similar) and comfort using modern AI tools - Strong mathematical and statistical aptitude, with a process- and systems-level mindset - Excellent attention to detail and clear written and verbal communication - Driven, creative, and persistent, with a willingness to go above and beyond and to work both independently and collaboratively in a fast-paced environment - Willingness to relocate from Union City, CA to Austin, TX in summer 2027 Preferred Qualifications: - Start-up experience - Previous automation or clinical laboratory experience - Experience with next-generation sequencing (NGS) and library preparation - Experience in a cell-free DNA setting - Prior experience with technology transfer, assay validation, or new lab/site standup Required Skills: Molecular biology techniques, PCR, DNA extraction, RNA extraction, Sequencing, Bioinformatics, Statistical analysis, Assay validation, Technology transfer, Laboratory automation, Analytical reasoning Benefits: Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%, Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%), Free UNITY Complete NIPT testing for employees & spouses, Supplemental fertility benefits coverage, Retirement savings program including a 4% Company match, Increase paid time off with increased tenure, Latest and greatest hardware (laptop, lab equipment, facilities), Free daily on-site lunches provided from top eateries, A variety of perks on campus (state of the art gym, restaurant), Free on-site EV charging (compatible with all EVs, including Tesla), Generous equity options offering, Corporate bonus program, Industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.)