US Site Engagement Lead at AstraZeneca in Remote

This field-based role is responsible for ensuring the local implementation of the operational site relationship management strategy (incl partner in care) for SMM Oncology at AstraZeneca. The individual will work collaboratively with business stakeholders to position AstraZeneca as the Sponsor of Choice for clinical sites. This role will require influential leadership skills and effective collaboration and partnership with sites, clinical, legal, contracts, CRO partners and other functions within AstraZeneca to develop and manage a best-in-class site relationship model that will allow to shorten study start-up timelines and increase site patient delivery.

Typical Accountabilities

• Implement and maintain Partner In Care strategies and activities with selected sites. Attend internal PiCN workgroups and discussion sessions. Work with AZ PiCN to coordinate presentations and discussion on AZ study portfolio and site inclusion.
• Establish strategic partnership models and framework to be deployed across key clinical sites through fit for purpose contracts, agreements and governance models.
• Strengthen relationship between sites and AZ clinical teams to enhance performance and overcome roadblocks in site start-up and execution and thereby becoming a partner of choice for the sites.
• Collaborate with local teams across different TAs to actively pursue resolution to study level challenges.
• Develop and maintain a working knowledge and materials of site processes and institution knowledge to guide study teams and leadership to positive decisions related to site inclusion and study management.
• Define and monitor site performance using objective measurements. Develop site relationship oversight model and state of the art tools and informatics. Manage site interactions effectively to ensure alignment of site and business expectations.
• Using available data sources, review site performance to identify trends and opportunities. Utilize this information with both local and external stakeholders to drive performance.
• Actively monitor and report study level metrics for activation and recruitment.
• Monitor delivery on site partnership agreements, identify challenge areas and implementation action to drive success.
• Routinely update TA DSMM or manager on site performance status.
• Escalate study or site issues to TA DSMMor manager if not resolved within a reasonable timeframe.
• Gain a clear understanding of the site team needs and communicate that within Leadership Team or manager.
• Lead the establishment and evaluation of site related business processes including development of new SOPs & work practices, ensuring consistency in site management policies and procedures.
• Demonstrate comprehensive understanding of site networks and business practices and the competitive clinical trial landscape in order to advise clinical teams on study specific site selection or site management strategies. Support local feasibility lead and LSAD in site identification and selection. Provide cross study knowledge sharing with applicable internal teams when appropriate.
• Propose and drive efficiency opportunities at the site level and within the SMM team interactions with the site during start-up and management activities.
• Collaborate with local medical affairs team (including MSL) to conduct mutual site exchanges to create a “OneAZ” mentality and support site success.
• Meet regularly with sites in coordination with local medical affairs (including MSL) and Global Site Lead.
• Contribute to process improvements, knowledge transfer and best practice sharing.

Minimum Qualifications:

• Bachelor degree in related discipline, preferably in life science, or equivalent qualification.
• Minimum 3 years of experience in Clinical Operations (CRA, SrCRA) or other related fields (Medical Affairs-led or Academic-led studies).
• Good knowledge of international guidelines ICH- GCP as well as relevant local regulations.
• Proven experience in building and developing relationships with key institutions.
• Excellent customer management skills.
• Good understanding and keen interest in digital solution and technology.
• Excellent organisational skills and ability to prioritize and handle multiple tasks.
• Excellent verbal and written communication skills.
• Excellent attention to details.
• Excellent knowledge of spoken and written English.
• Good negotiation skills and influential leadership skills.
• Good ability to learn and to adapt to work with IT systems.
• Excellent problem solving and conflict resolution skills.
• Ability to look for and champion more efficient and effective methods/processes of delivering clinical trials to plan focusing on key performance metrics of speed, quality, and cost.
• Manages change with a positive approach to the challenges of change for self, team and the business. Sees change as an opportunity to improve performance and add value to the business.
• Ability to work across various studies and indications, collaborate with multiple LSTs and GSTs, as needed.
• Integrity and high ethical standards.
• Ability to travel nationally as required.

Desirable Qualifications:

• Good medical knowledge and ability to learn relevant AZ Therapeutic Areas.
• Good knowledge of the Drug Development Process.
• Excellent understanding of the Clinical Study Process including monitoring.
• Very good understanding of the Study Drug Handling Process and the Data Management Process.
• Good analytical skills.
• Good decision making skills.
• Basic ability in handling crisis situations.
• Ability to influence strategically and persuade tactfully, to obtain desired outcomes while maintaining effective, positive, organizational relationships.
• Knowledge of the latest technical and regulatory expectations.
• Familiarity with the latest research and thinking.
• Experience in Oncology area.

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next? 

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you!

The annual base pay for this position ranges from $137,937.60 - $206,906.40 USD Annual . Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

28-Apr-2026

Closing Date

12-May-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.