INTERN

Summary: Sanford Burnham Prebys is focused on exploring the role of norepinephrine in cellular function related to neurodegenerative diseases. The intern will engage in hands-on research, focusing on genetic variations and their influence on cellular responses, while gaining experience in various assays and data analysis. Responsibilities: - Actively work/engage in experimental design and analytical components of the project - Document progress that is done with each experiment (mini progress reports) - Meet with mentor daily to go over experimental design, planning, data review, and tracking progress - Provide weekly updates during lab meetings; communicate my understanding of the material, show progress, and receive feedback - Analyze and interpret data with normalization and statistical methods - Generate publication-quality figures and learn to clearly communicate those findings (written reports + oral presentation) Required Qualifications: - Hands-on experience working with several different assays and maintaining iPSC-derived cultures - Ability to perform calcium mobilization assays using purinergic stimulation - Experience assisting with immunofluorescence assays (IFAs) - Skills in performing gene expression analyses - Ability to actively work/engage in experimental design and analytical components of the project - Capability to document progress with each experiment (mini progress reports) - Willingness to meet with mentor daily to go over experimental design, planning, data review, and tracking progress - Ability to provide weekly updates during lab meetings - Skills to analyze and interpret data with normalization and statistical methods - Ability to generate publication-quality figures and communicate findings clearly (written reports + oral presentation) - Ability to perfect at least two of the following skills: ELISA, IFA, calcium mobilization, etc - Availability to work a minimum of 20 hours a week in the lab - Skills in designing a project, experiment design and timelines - Ability to produce a final written report with background, methods, results, and interpretation of the work done - Ability to deliver a final presentation summarizing the report, connecting it back to neurodegenerative diseases and neuromodulatory signaling Required Skills: ELISA, Immunofluorescence Assays, Calcium Mobilization Assays, Gene Expression Analysis, iPSC-derived Cell Culture, Experimental Design, Statistical Methods, Data Interpretation